02.08.2019, 20:12
The Main Cause of Cancer is Named
Source: OREANDA-NEWS
OREANDA-NEWS Dysfunction of the TP53 gene, which is responsible for stunting and cell division during damage or stress, is the main cause of cancer. This is stated in the results of a study published on the EurekAlert! Portal.
Scientists at Baylor College of Medicine in the United States studied 10,225 tissue samples representing 32 types of cancerous tumors, and compared their DNA with 80,000 different mutations, which were collected over three decades of research. It turned out that patients with low survival often had mutations in the gene.
In addition to the role of TP53 in the development of cancer, the researchers found four more genes that affect patient survival. In addition, the analysis showed that in 91 percent of the studied cases of cancer, defects were observed in both copies of the TP53 gene, which most often occurred due to duplication of the first defective copy.
Scientists at Baylor College of Medicine in the United States studied 10,225 tissue samples representing 32 types of cancerous tumors, and compared their DNA with 80,000 different mutations, which were collected over three decades of research. It turned out that patients with low survival often had mutations in the gene.
In addition to the role of TP53 in the development of cancer, the researchers found four more genes that affect patient survival. In addition, the analysis showed that in 91 percent of the studied cases of cancer, defects were observed in both copies of the TP53 gene, which most often occurred due to duplication of the first defective copy.
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