OREANDA-NEWS. Glia, a collection of non-neuronal cells that have long been regarded as passive support cells, may in fact play a vital role in nerve-cell development in the brain.

The finding, which was somewhat unexpected, offers new insights into the building of the nervous system.

“The results lead us to revise the often neuro-centric view of brain development to now appreciate the contributions for non-neuronal cells such as glia,” explains Vilaiwan Fernandes, a postdoctoral fellow in the biology department at New York University and the study’s lead author.

“Indeed, our study found that fundamental questions in brain development with regard to the timing, identity, and coordination of nerve cell birth can only be understood when the glial contribution is accounted for,” she says.

The brain is made up of two broad cell types, nerve cells or neurons and glia, which are non-nerve cells that make up more than half the volume of the brain. Neurobiologists have tended to focus on the former because these are the cells that form networks that process information.

Given the preponderance of glia in the brain’s cellular make-up, however, the researchers hypothesized that they could play a fundamental part in brain development.